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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFKB1 All Species: 28.79
Human Site: S684 Identified Species: 57.58
UniProt: P19838 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19838 NP_003989.2 968 105356 S684 V N A Q E Q K S G R T A L H L
Chimpanzee Pan troglodytes XP_001168657 976 106346 S692 V N A Q E Q K S G R T A L H L
Rhesus Macaque Macaca mulatta XP_001109228 968 105518 S684 V N A Q E Q K S G R T A L H L
Dog Lupus familis XP_862878 904 96875 G638 V E A A E R Q G G R T A L H L
Cat Felis silvestris
Mouse Mus musculus P25799 971 105623 S680 V N A Q E Q K S G R T P L H L
Rat Rattus norvegicus Q63369 522 56535 G255 A G C L L L E G D A L V D S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514381 266 29283
Chicken Gallus gallus Q04861 984 108151 S682 V N A Q E Q K S G R T A L H L
Frog Xenopus laevis O73630 958 105836 S644 V N S A E R K S G K S P L H I
Zebra Danio Brachydanio rerio NP_001001840 902 98760 S632 I N M P E Q K S G C T A L H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P15330 999 111533 A687 P V P P V P P A I L T I Q Y P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999819 1125 124026 T804 V N V A D G K T G R T A L H Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.7 42.9 N.A. 86.7 47.3 N.A. 26 71.6 39.3 40.1 N.A. 22.8 N.A. N.A. 35.7
Protein Similarity: 100 99.1 99.1 56.8 N.A. 91.8 50.3 N.A. 27 82.7 56.2 54.4 N.A. 38.7 N.A. N.A. 52
P-Site Identity: 100 100 100 66.6 N.A. 93.3 0 N.A. 0 100 53.3 73.3 N.A. 6.6 N.A. N.A. 60
P-Site Similarity: 100 100 100 80 N.A. 93.3 6.6 N.A. 0 100 86.6 80 N.A. 20 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 50 25 0 0 0 9 0 9 0 59 0 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 9 0 0 0 9 0 0 % D
% Glu: 0 9 0 0 67 0 9 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 9 0 17 75 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 75 0 % H
% Ile: 9 0 0 0 0 0 0 0 9 0 0 9 0 0 9 % I
% Lys: 0 0 0 0 0 0 67 0 0 9 0 0 0 0 0 % K
% Leu: 0 0 0 9 9 9 0 0 0 9 9 0 75 0 59 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 9 17 0 9 9 0 0 0 0 17 0 0 9 % P
% Gln: 0 0 0 42 0 50 9 0 0 0 0 0 9 0 0 % Q
% Arg: 0 0 0 0 0 17 0 0 0 59 0 0 0 0 0 % R
% Ser: 0 0 9 0 0 0 0 59 0 0 9 0 0 9 0 % S
% Thr: 0 0 0 0 0 0 0 9 0 0 75 0 0 0 9 % T
% Val: 67 9 9 0 9 0 0 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _